Product Name :
PI 3 Kinase p85 beta Recombinant Rabbit Monoclonal Antibody [ST04-77]
Predicted band size :
82 kDa
Observed band size :
82 kDa
Synonyms:
p85 antibody p85 beta antibody P85B antibody P85B_HUMAN antibody Phosphatidylinositol 3 kinase antibody Phosphatidylinositol 3 kinase regulatory beta subunit antibody Phosphatidylinositol 3 kinase regulatory subunit beta antibody Phosphatidylinositol 3 kinase regulatory subunit polypeptide 2 antibody Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta) antibody Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta antibody 展开
Function :
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110α expression is restricted to white blood cells. It has been shown to bind p85α and p85β, but it apparently does not phosphorylate these subunits. p110α seems to have the capacity to autophosphorylate. p110α does not interact with the p85 subunits. It has been shown to be activated by α and β heterotrimeric G proteins.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PI 3 Kinase p85 beta aa 136-185 / 728.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Coupling :
unconjugated
Clone number:
ST04-77
RRID:
AB_3069841
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Buy1,2-Oxathiolane 2,2-dioxide Aliquot store at -20℃ or -80℃.m-PEG12-acid uses Avoid repeated freeze / thaw cycles.PMID:33624550
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 82 kDa
Positive control :
Raji cell lysate, Hela cell lysate, MCF-7 cell lysate, U937 cell lysate, PC-12 cell lysates, Hela, SHG-44, rat testis tissue, rat brain tissue, NIH/3T3 cell lysates.