Product Name :
SSBP1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
mitochondrial antibody Mt SSB antibody Mt-SSB antibody MtSSB antibody PWP1 interacting protein 17 antibody PWP1-interacting protein 17 antibody SENSOR OF SINGLE-STRANDED DNA COMPLEX antibody Single stranded DNA binding protein 1 antibody Single stranded DNA binding protein antibody Single stranded DNA binding protein mitochondrial antibody 展开
Function :
Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA). In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays crucial roles during mtDNA replication that stimulate activity of the replisome components POLG and TWNK at the replication fork. Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity.2445347-90-8 Chemscene In addition it is able to promote the 5′-3′ unwinding activity of the mtDNA helicase TWNK.5-Fluorobenzofuran-2-carboxylic acid uses May also function in mtDNA repair.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human MtSSB.PMID:33709138 AA range:99-148
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
17 kDa
Positive control :
Amygdala,Brain,Cervix,Prostate,