Product Name :
UCP-1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
mitochondrial brown fat uncoupling protein antibody Mitochondrial brown fat uncoupling protein 1 antibody SLC25A7 antibody Solute carrier family 25 member 7 antibody Thermogenin antibody UCP 1 antibody UCP antibody UCP1 antibody UCP1_HUMAN antibody uncoupling protein 1 (mitochondrial 展开
Function :
Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs.2413767-30-1 site Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP.368866-07-3 Formula Regulates the production of reactive oxygen species/ROS by mitochondria.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human UCP-1 101-200/307
Species reactivity:
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
Verify application:
WB, ELISA, FC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.PMID:33517556 Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
33 KDa
Positive control :
Brown adipose tissue, Mouse spleen, Thymus (Mouse) Lysate.