Product Name :
2-Deoxy-2-fluoro-D-glucose (CAS 29702-43-0)
Synonym :
2-Deoxy-2-fluoro-D-glucose is also known as FDG.
Application :
2-Deoxy-2-fluoro-D-glucose is a cellular glycosylation inhibitor.
CAS:
29702-43-0
Purity:
Molecular Weight:
182.15
Formula :
C6H11FO5
Physical state:
Solid
solubility :
Soluble in water, and methanol.
Shipping Condition :
Store at -20° C
Melting point:
174-176° C
SMILES:
C(C1C(C(C(C(O1)O)F)O)O)O
References:
:History of the first synthesis of 2-deoxy-2-fluoro-D-glucose the unlabeled forerunner of 2-deoxy-2-[18F]fluoro-D-glucose. | Pacák, J. and Cerný, M. 2002. Mol Imaging Biol. 4: 352-4. PMID: 14537109Retinoblastoma treatment: utilization of the glycolytic inhibitor, 2-deoxy-2-fluoro-D-glucose (2-FG), to target the chemoresistant hypoxic regions in LH(BETA)T(AG) retinal tumors. | Piña, Y., et al. 2012. Invest Ophthalmol Vis Sci. 53: 996-1002. PMID: 22266512Distribution of 2-deoxy-2-fluoro-d-glucose in the coelom of healthy bald eagles (Haliaeetus leucocephalus). | Jones, MP., et al. 2013. Am J Vet Res. 74: 426-32. PMID: 234381182-Deoxy-2-fluoro-d-glucose metabolism in Arabidopsis thaliana. | Fatangare, A., et al. 2015. Front Plant Sci. 6: 935. PMID: 26579178Applications of 2-deoxy-2-fluoro-D-glucose (FDG) in Plant Imaging: Past, Present, and Future. | Fatangare, A. and Svatoš, A. 2016. Front Plant Sci. 7: 483. PMID: 27242806Positron Emission Tomography Fluorine-18-Labeled 2-Deoxy-2-Fluoro-d-Glucose Tells a Complicated Story in the Aortic Aneurysm Wall. | Curci, JA. and Beckman, JA. 2016. Circ Cardiovasc Imaging. 9: PMID: 27903546Non-radioactive 2-deoxy-2-fluoro-D-glucose inhibits glucose uptake in xenograft tumours and sensitizes HeLa cells to doxorubicin in vitro. | Niccoli, S., et al. 2017. PLoS One. 12: e0187584. PMID: 29095925Metabolic pathway of 2-deoxy-2-fluoro-D-glucose studied by F-19 NMR. | Kanazawa, Y., et al. 1986. Life Sci. 39: 737-42. PMID: 3736344A short synthesis of 2-deoxy-2-fluoro-D-glucose.1612792-88-7 Price | Kovác, P.2-Chloro-4-methylpyrimidin-5-amine structure 1986.PMID:33752995 Carbohydr Res. 153: 168-70. PMID: 3779690Lysis of Saccharomyces cerevisiae with 2-deoxy-2-fluoro-D-glucose, an inhibitor of the cell wall glucan synthesis. | Biely, P., et al. 1973. J Bacteriol. 115: 1108-20. PMID: 4580558A comparison of the toxic effects of 2-deoxy-D-glucose and 2-deoxy-2-fluoro-D-hexoses on Saccharomyces cerevisiae cells and protoplasts. | Biely, P., et al. 1981. Z Allg Mikrobiol. 21: 489-97. PMID: 70343852-Deoxy-2-fluoro-D-glucose as a functional probe for NMR: the unique metabolism beyond its 6-phosphate. | Kanazawa, Y., et al. 1996. J Neurochem. 66: 2113-20. PMID: 878004319F NMR of 2-deoxy-2-fluoro-D-glucose for tumor diagnosis in mice. An NDP-bound hexose analog as a new NMR target for imaging. | Kanazawa, Y., et al. 1997. NMR Biomed. 10: 35-41. PMID: 9251114